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ISO 13485 Quality Manual

Table of Contents

Section 1: Welcome to (Your Co)
Section 2: Company Vision and Governing Policies
Section 3: Scope, Exclusions and Definitions
Section 4: Quality Management System
Section 5: Management Responsibility
Section 6: Resource Management
Section 7: Product Realization
Section 8: Measurement, Analysis, & Improvement
Appendix A: Company Processes and Applicable Clauses
Appendix B: Company Processes and Applicable Documents
Appendix C: Outsourced Processes
Appendix D: Quality Objectives
Appendix E: Identification of Key Product Realization Processes

Section 1:    Welcome to (Your Company Name)

The Company is a developer and producer of medical devices that include (your product description).
The Company has always applied...
The Company is dedicated to...

Section 2:    Company Vision and Governing Policies

...

Section 3:    Scope, Exclusions and Definitions

3.1    Scope
The Company's quality management system applies to...
The Company's scope of business is defined as follows:
...

3.2    Exclusions
The Company cites...

3.3    Definitions & Conventions
Unless otherwise noted, the Company applies the definitions of key terms according to ISO 13485 and...

Section 4:    Quality Management System

4.1    General Requirements

4.1.1 The Company's quality system... (see the Management Process Procedure) and to meet the requirements of...

The Company has... and emphasizes the importance of:

  1. ...
  2. ...
  3. ...
  4. ...

4.1.2 For each process identified in use at the Company (see the Management Process Procedure), the sequence and interaction of processes has...

Every process...

...

4.1.3 Processes are...

  • ...
  • ...
  • ...

4.1.4 The Company manages quality management system processes and procedures according...

Changes ... are controlled according to the Configuration Management Procedure and are:

  • ...
  • ...
  • ...

4.1.5 When the Company elects to outsource..., The controls for outsourced activities are... according to the Purchasing Procedure, which includes...

4.1.6 The Company controls... according to the Production Procedure, and after... Records of validations are retained and maintained according to the Control of Documented Information Procedure.

4.2    Documentation Requirements
The quality system documentation is...
All documents support and...

Figure 1:

...

4.2.1    General
Documentation for the Company's quality management system includes:

  1. ...
  2. ...
  3. ...
  4. ...

The order of precedence of order-specific documentation is as follows...:

  1. ...
  2. ...
  3. ...
  4. ...
  5. ...

4.2.2    Quality Manual
The primary purpose of the Quality Manual and QMS Procedures is... according to the Configuration Management Procedure. Additional procedures and work instructions...

  1. ...
  2. ...
  3. ...

4.2.3    Medical Device File
For each medical device type or medical device family, the Company...

The contents of the medical device file includes:

  1. ...
  2. ...
  3. ...
  4. ...
  5. ...
  6. ...

4.2.4    Control of Documents
The controls for documents are defined in Control of Documented Information Procedure

Documents are controlled to:

  1. ...
  2. ...
  3. ...
  4. ...
  5. ...
  6. ...
  7. ...
  8. ...

Changes to documents are... according to the Configuration Management Procedure.

Obsolete documents are retained and maintained according to the Control of Documented Information Procedure.

4.2.5    Control of Records
Records are controlled to provide... Records subject to control are defined in the Control of Documented Information Procedure.

Section 5:    Management Responsibility

5.1    Management Commitment
The Company is committed... according to the Management Process Procedure and the following...:

  1. ...
  2. ...
  3. ...
  4. ...
  5. ...

5.2    Customer Focus
The Company demonstrates leadership and commitment with respect... Management pays particular attention... according to the Management Process Procedure. Applicable regulatory/statutory requirements are... according to the Proposal Development and Contract Review Procedure.

5.3    Quality Policy
The Company's Quality Policy is defined in Section 2.0, which is... according to the Management Process Procedure. The Quality Policy is... according the Control of Documented Information Procedure. The Quality Policy may...

The Company's quality policy:

  1. ...
  2. ...
  3. ...
  4. ...
  5. ...

5.4    Planning

5.4.1    Quality Objectives
Every process within the Company has... Objectives are derived from... Objectives are subject to... The table in Appendix D defines the quality objectives in place at the Company. Quality objectives are... published in... - see the Management Process Procedure.

5.4.2    Quality Management System Planning
... the Company's size and complexity are... according to the Management Process Procedure.
Planning for the quality management system includes... The Management Process Procedure is used to... enable the Company to achieve...

The quality system has... Subsequent major changes... are... The QMS documentation acts as...
Changes to the quality management system are performed according to the Configuration Management Procedure, which considers...

5.5    Responsibility, Authority and Communication

5.5.1    Responsibility and Authority
The organizational chart in Figure 2 defines ... In all cases, ... which are further defined in the Responsibilities and Authorities Procedure. All Employees are empowered to...

Figure 2: Responsibilities and Authorities

...

5.5.2    Management Representative
The Quality Manager of the Company has been assigned the role of Quality System Management Representative... The Quality Manager is responsible for..., as well as for...

The Quality Manager reports directly to...

The Quality Manager has the responsibility and authority to...

5.5.3    Internal Communication
To ensure proper communication between and throughout all levels of Employees within the Company, internal communication... according to the Management Process Procedure. Management holds... Employees are encouraged to use the Request for Support form... according to the Control of Nonconformities Procedure.

5.6    Management Review

5.6.1    General
Management Review meetings are conducted according to the Management Process Procedure, which defines...

5.6.2    Review Input
See the Management Process Procedure for details regarding review inputs.

5.6.3    Review Output
See the Management Process Procedure for details regarding review outputs.

Section 6:    Resource Management

6.1    Provision of Resources
During management review, the Company's management...

The processes of Management and Proposal Development and Contract Review have... Employees may submit the Request for Support form to... Resource management is addressed in the Management Process Procedure.

6.2    Human Resources

Employees are... Personnel undergo training... according to the Training Program.

All Company personnel are... according to the Training Program.

The Company's training program:

  1. ...
  2. ...
  3. ...
  4. ...
  5. ...

The training program is defined in the Training Program.

6.3    Infrastructure
The Company has determined and provided...

Infrastructure requirements are regularly reviewed during Management Review and include a review of:

  • ...
  • ...
  • ...
  • ...

The Company utilizes maintenance routines... Records of maintenance activities are retained and maintained according to the Control of Documented Information Procedure. Monitoring and measurement equipment is controlled according to the Calibration Procedure. The Facilities Manager... IT resources are... For more on management's controls over the infrastructure, see the Management Process Procedure.

6.4    Work Environment and Contamination Control
The Company has determined and provided... For more on management's controls over the work environment, see the Management Process Procedure.

6.4.1    Work Environment
The Company documents requirements to monitor and control the work environment when...

The Company:

  1. ...
  2. ...

6.4.2    Contamination Control
To prevent contamination of the work environment,...

For sterile medical devices, the Company documents:

  1. ...
  2. ...

6.5    Corrective Maintenance
The Company utilizes corrective maintenance and skilled maintenance personnel to... Preventive maintenance activities are... It is acceptable to...

Section 7:    Product Realization

7.1    Planning of Product Realization
In planning the processes for product realization, the Company... during Proposal Development and Contract Review...

  1. ...
  2. ...
  3. ...
  4. ...

7.2    Customer-Related Processes

7.2.1    Determination of Requirements Related to Product
The Company determines..., which is defined in the Proposal Development & Contract Review Procedure, and includes:

  1. ...
  2. ...
  3. ...
  4. ...

7.2.2    Review of Requirements Related to Product

Once requirements are... as defined in the Proposal Development & Contract Review Procedure, which includes:

  1. ...
  2. ...
  3. ...
  4. ...
  5. ...

Where the Customer provides...

When product requirements are changed, the Company... according to the Configuration Management Procedure.

Records... are retained and maintained according to the Control of Documented Information Procedure

7.2.3    Communication
The Company..., which includes:

  1. ...
  2. ...
  3. ...
  4. ...
  5. ...

Communication methods may include...

7.3    Design and Development

7.3.1    General
The Design and Development process... is defined in the Design and Development Procedure, which includes provisions for...:

  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...

7.4    Purchasing
Purchasing is... fully defined in the Purchasing Procedure.

7.4.1    Purchasing Process
The purchasing process... The Company determines that purchased product... according to the Receiving Procedure.

The criteria applied for the evaluation and selection of Suppliers is:

  1. ...
  2. ...
  3. ...
  4. ...

The Company monitors Supplier performance... according to the Receiving Procedure taking into account...
Records of the results... are... according to the Control of Documented Information Procedure.

7.4.2    Purchasing Information
Purchase orders are used...

Purchasing information..., including as appropriate:

  1. ...
  2. ...
  3. ...
  4. ...

The Company... see the Purchase Order Review Work Instruction.
Purchasing information includes... The Company retains and maintains purchasing documents, Supplier surveys and records according to the Control of Documented Information Procedure.

7.4.3    Verification of Purchased Product
Incoming materials are... as defined in the Receiving Procedure.

..., the Company determines... according to the Management Process Procedure.

...external provider... according to the Receiving Procedure.

7.5    Production and Service Provision

7.5.1    Control of Production and Service Provision
Production and services are... according to the Production Procedure ..., which includes:

  1. ...
  2. ...
  3. ...
  4. ...
  5. ...
  6. ...s

The Company has established and retains/maintains...

7.5.1.1    Production Documentation
Production operations are... In addition, the Company... These activities are fully defined in the Production Procedure and the Design and Development Procedure.

7.5.1.2    Control of Production Process Changes
Only the Configuration Control Board (CCB)... are fully defined in the Production Procedure and the Design and Development Procedure.

7.5.1.3    Control of Production Equipment & Tools
Production equipment and tools are... according to the Production Procedure. The Internal Auditing Procedure confirms...

7.5.1.4    Control of Work Transferred on a Temporary Basis Outside the Organization's Facilities
When the Company provides supplies for outside processing,... work is performed under the following controls:

  • ...
  • ...
  • ...
  • ...

7.5.1.5    Control of Service Operations
The Company services supplies...

7.5.2    Cleanliness of Product
The Company produces documented information for cleanliness of product... according to the Production Procedure, when:

  1. ...
  2. ...
  3. ...
  4. ...
  5. ...

If product is cleaned according to a) or b) above, the requirements.. do not...

7.5.3    Installation Activities
The Company produces documented information... according to the Proposal Development and Contract Review Procedure.

If the agreed Customer requirements..., the Company provides...

Records of medical device... according to the Control of Documented Information Procedure.

7.5.4    Servicing Activities
When servicing of a medical device is required, the Company... according to the Proposal Development and Contract Review Procedure.

The Company analyses records of servicing activities produced by itself and its Suppliers:

  1. ...
  2. ...

Records of servicing activities are retained and maintained according to the Control of Documented Information Procedure.

7.5.5    Particular Requirements for Sterile Medical Devices
The Company retains and maintains records... according to the Control of Documented Information Procedure, which are...

7.5.6    Validation of Processes for Production and Service Provision
The Company validates production and service processes... according to the Production Procedure.

Records of the results and conclusion of validation and necessary actions from the validation are retained and maintained according to the Control of Documented Information Procedure.

7.5.7    Particular Requirements for Validation of Processes for Sterilization and Sterile Barrier Systems
The Company produces... according to the Production Procedure.

...

7.5.8    Identification
The Company produces documented information for product identification... according to the Production Procedure.

The Company identifies... throughout product realization.

If required..., the Company... according to the Production Procedure.

Returned medical devices... according to the Control of Nonconformities Procedure.

All products..., which is fully defined in the Production Procedure

7.5.9    Traceability

7.5.9.1    General
The Company produces documented information for traceability... according to the Production Procedure. Records of traceability are retained and maintained according to the Control of Documented Information Procedure.

7.5.9.2    Particular Requirements for Implantable Medical Devices
Traceability requirements include... according to the Production Procedure.

The Company requires Suppliers...

7.5.10    Customer Property
Customer property is controlled according to the Receiving Procedure and the Production Procedure. ... Records produced for the control of Customer property are retained and maintained according to the Control of Documented Information Procedure.

7.5.11    Preservation of Product
The Responsible Authority... according to the Production Procedure.

Special conditions required for preservation of product are controlled according to the Production Procedure and are recorded according to the Control of Documented Information Procedure.

7.6    Control of Monitoring and Measuring Equipment
The Company determines the monitoring and measurement... according to the Production Procedure.

Equipment, tools,... according to the Production Procedure.

All measuring and test equipment instruments and devices... are maintained as defined in the Calibration Procedure.

To ensure valid measurement results, measuring equipment:

  1. ...
  2. ...
  3. ...
  4. ...
  5. ...

In addition, the Company...

When computer software is used in the monitoring and measurement of specified requirements,...

The specific approach and activities associated with software validation and revalidation...

Records of the results and conclusion of validation and necessary actions from the validation are retained and maintained according to the Control of Documented Information Procedure.

Section 8:    Measurement, Analysis and Improvement

8.1    General
Appropriate methods... according to the Management Process Procedure and the Production Procedure, which ensure the Company can:

  1. ...
  2. ...
  3. ...

When applicable,...

Responsible Authorities collect data for determining the acceptability of the quality management system, which may include:

  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...
  • ...

8.2    Monitoring and Measurement

8.2.1    Feedback
As one of the measurements of the effectiveness of the quality management system, the Company... according to the Management Process Procedure.

The Company's feedback process includes... Records are retained and maintained according to the Control of Documented Information Procedure.

8.2.2    Complaint Handling
The Company produces documented information for timely complaint handling according to... the Control of Nonconformities Procedure, which includes...

Justification is documented in the Request for Support form...
If an investigation determines...
Complaint handling records are retained and maintained according to the Control of Documented Information Procedure.

8.2.3    Reporting to Regulatory Authorities
When applicable regulatory requirements require notification of complaints... according to the Control of Nonconformities Procedure.

Records of reporting to regulatory authorities are retained and maintained according to the Control of Documented Information Procedure.

8.2.4    Internal Audit
Internal quality audits are... This is accomplished by... the Internal Auditing Procedure, which determines if the quality management system:

  1. ...
  2. ...

The audit program is... Records of the audits and their results are retained and maintained according to the Control of Documented Information Procedure. The Responsible Authority for the area being audited...

8.2.5    Monitoring and Measurement of Processes
Quality management system processes are...

The method for measuring process performance to demonstrate the ability of each process to achieve planned objectives is defined according to the Management Process Procedure. ...

8.2.6    Monitoring and Measurement of Product
The Company monitors and measures... according to the Production Procedure. ...

Evidence of conformity to the acceptance criteria is retained and maintained according to the Control of Documented Information Procedure, which...

For implantable medical devices, the Company...

8.3    Control of Nonconforming Product

8.3.1    General
All Supplier provided products, in-process products, final products and production processes... are... according to the Control of Nonconformities Procedure.

8.3.2    Actions in Response to Nonconforming Product Detected Before Delivery
Nonconforming product is... according to the Control of Documented Information Procedure.

Nonconformities are processed by:

  1. ...
  2. ...
  3. ...
  4. ...

When nonconforming product is corrected, it is... according to the Control of Documented Information Procedure.

8.3.3    Actions in Response to Nonconforming Product Detected After Delivery
The Company takes appropriate action... according to the Control of Nonconformities Procedure. Records of actions taken are retained and maintained according to the Control of Documented Information Procedure.

The Company applies requirements..., which are... Records of actions relating to the issuance of advisory notices are retained and maintained according to the Control of Documented Information Procedure.

8.3.4    Rework
The Company performs product rework/repair according to the Control of Nonconformities Procedure. ... Records of rework/repair are retained and maintained according to the Control of Documented Information Procedure.

8.4    Analysis of Data
The Company... according to the Management Process Procedure. The data is used... In addition,...

If the analysis of data.... Records of the results of analyses are retained and maintained according to the Control of Documented Information Procedure.

8.5    Improvement

8.5.1    General
It is the goal...

8.5.2    Corrective Action
The Company has implemented... according to the Corrective Action Procedure, which can...

Records of the results of any investigation and applied actions are retained and maintained according to the Control of Documented Information Procedure.

8.5.3    Preventive Action
In addition to the preventive measures taken for corrective actions... according to the Corrective Action Procedure.

Records of the results of any investigation and applied actions are retained and maintained according to the Control of Documented Information Procedure.

Appendix A: Company Processes and Applicable ISO 13485 Clauses

...

Appendix B: Company Processes and Applicable Documents

Process Applicable Company QMS Procedure Applicable Records
... ... ...

Appendix C: Outsourced Processes

The following processes are outsourced and controlled as indicated:

  • ...
  • ...
  • ...

Appendix D: Quality Objectives

Process Quality Objective Metric
... ... ...

Appendix E: Identification of Key Realization Processes

...

9.0 REVISION HISTORY AND APPROVAL RECORD

Quality System Procedure
QUALITY MANUAL
Rev: Orig (EO #101)

PROPRIETARY INFORMATION - UNCONTROLLED IF PRINTED UNLESS OTHERWISE MARKED